Hyperdilute Radiesse: How It Differs from Radiesse
If you are new to the world of biostimulatory fillers, this is why we love Radiesse: in its traditional formulation, it has both an immediate filling effect, noticeable directly after injection, while also triggering collagen stimulation over time.
In other words, Radiesse combines the best parts of traditional and biostimulatory fillers—making it one of the most adaptable tools in regenerative aesthetics.
At FACE, we inject Radiesse in 3 different forms, each of which has unique features and benefits. Learn about why we dilute Radiesse, what happens when we do, and why it might be the right treatment for some of your skin rejuvenation needs.
ON-LABEL RADIESSE
On-Label Radiesse is the product in its standard formulation, without any added fluids. This is the thick, viscous product which is FDA-approved for volume replacement and lift in the face and hands.
Structured like a high-viscosity filler, on-label Radiesse is made of calcium-based microspheres in a gel carrier. When injected, the CaHA particles restore lost volume beneath the skin while causing your body to restore its own collagen over time, which helps smooth skin and keep your results looking fresh.
On-label Radiesse is ideal for:
Facial contouring and lifting
Hand rejuvenation
Patients looking for both visible volume changes plus collagen growth
DILUTE RADIESSE
Dilute Radiesse refers to the full-strength product thinned with a small amount of saline. When Radiesse is mixed with sterile fluid, the calcium-based particles start to lose some of their structural integrity, making the solution more flexible.
After it has been diluted, Radiesse still provides a small bit of lift and skin tightening, but as we thin the product, it starts to function more like a biostimulator than a traditional filler.
Dilute Radiesse works well for:
Mild skin laxity
Patients who want a little lift plus long-term collagen stimulation
HYPERDILUTE RADIESSE
Finally, hyperdilute Radiesse is an even thinner version of the injectable that has been mixed with a higher ratio of sterile fluid. In its hyperdilute form, Radiesse flows like a thin liquid that acts like a true biostimulator, rather than a filler.
Hyperdilute Radiesse has the power to increase your skin’s natural collagen and elastin production to target skin texture issues like fine lines and wrinkles, creating a firmer, healthier-looking complexion.
Hyperdilute Radiesse is often used for:
Moderate skin laxity
Skin rejuvenation and firming
Skin texture issues like fine lines
RADIESSE VS. DILUTE VS. HYPERDILUTE RADIESSE
| Product | Made of | Primary Effects | Best For |
|---|---|---|---|
| Radiesse (On-Label) | CaHA in gel carrier (high viscosity) | Immediate volume and lift plus collagen stimulation | Cheeks, jawline, hands |
| Dilute Radiesse | CaHA mixed with small amount of sterile liquid | Mild lift plus bio-stimulation | Mild laxity, early volume loss |
| Hyperdilute Radiesse | CaHA with more sterile liquid (low viscosity) | Bio-stimulatory only: improves skin texture, firmness, tone | Neck, chest, arms, knees, crepey skin |
Biostimulatory Filler Skin Care Products
Strategy & Writing by
Ella Marcantonio
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